KANG-HSI WU2026-10-162026-10-162002-10-01Pure ID: 15271714Pure UUID: 58809591-359d-43fb-89c9-f5ee9094de5810.1046/j.1365-3148.2002.00394.xhttps://www.scopus.com/pages/publications/0036793344https://scholars.csmu.edu.tw/handle/123456789/24432Anti-'Mia'is the most common alloantibody of potential clinical significance in the Taiwanese population. The Mi.III phenotype is rare among Caucasians but has a high incidence in various Oriental populations. We describe a nulliparous woman with no history of transfusions, who had hydrops foetalis at 28 weeks gestation. Foetal haemoglobin was 4.4gdL-1, and a positive direct antiglobulin test was positive in the foetal blood. Intrauterine intravascular transfusion was given, and the baby was discharged healthy. Anti-'Mia' was identified in the maternal serum, the cord blood serum and the eluate from red cells of the cord blood. Anti-'Mia' in the maternal serum was confirmed to be anti-Mur. The polymerase chain reaction-restriction fragment length polymorphism method confirmed that both the baby and her father had the Mi.III gene. Therefore, our report documents that anti-Mur has the potential to cause hydrops foetalis.3enjournal article