2026-11-092026-11-09https://scholars.csmu.edu.tw/handle/123456789/38435The chlorophenols pollutants exists in the environment extensively, human body and them contact the chance and increase being relative, such them may invade the human body via different ways , such as eat, suck or permeated the human body by the skin, and cause the injury to the health. The ration of the sample of the trace concentration of the carcinogenic material is determined, has been limited to all the time that analytical method and survey of the instrument have detecting and examining the factor that limit can't be reduced, must often cause and interfere the missing of the increase or sample of the situation through heavy and complicated drawing back and dealing with the course thick , make staff members of the experiment increase and expose in the harmful danger of the carcinogen very much of solvent too. How be can thick to contract way determined , analytical technology of sample one urgent essential and important work in trace concentration by a continuous one directly. This study to finish in order to utilize microdialysis technology and cooperating with HPLC-UV with in three years. Contain the chlorophenols to the labourer workplace air is 1-chlorophenol, 2,4- dichlorophenol, 2,4,6- trichlorophenol, 2,3,4,6-tetrachlorophenol and pentachlorophenol. This technology will be a kind of analytical method with fast , economy , environmental protection , security , cooperate and probe into HPLC-UV and analyze the condition , analyze precision and accuracy , sample and assess , the method detects and examines limit , examining amount line range , analyses the stability and interfering the factor etc..氯酚污染物廣泛存在於環境中，人體與氯酚污染物接觸機會將相對增加，如此氯酚 可能經由不同途徑入侵人體，如吞食、吸入或由皮膚滲入人體，而對人體健康造成傷害。 致癌性物質的微量濃度之樣品定量測定，一直受限於分析方法與儀器之測定偵測極 限無法降低的因素，必須透過繁複的濃縮處理過程，往往造成干擾情形的增加或是樣品 的漏失，也使實驗的工作人員增加暴露於有害溶劑極致癌物質的危害，如何能直接以連 續的濃縮方式加以測定，在微量濃度樣品的分析技術是一項急迫必要且重要的工作。 .研究擬以三年計畫完成以利用微透析技術配合HPLC -UV 的分離鑑定技術，針 對勞工作業環境空氣中含有氯酚(Chlorophenol)、2,4-二氯酚(2,4-Dichlorophenol) 、2,4,6- 三氯酚(2,4,6-Trichlorophenol)、2,3,4,6-四氯酚(2,3,4,6-Tetra chloro- phenol)、五氯酚 (Pentachlorophenol)等五種分別為含1 個氯至五個氯的氯酚類進行採樣測定的研究。此技 術將是一種具快速、經濟、環保、安全之分析方法，配合探討HPLC-UV 分析條件、分 析精密度與準確度、採樣評估、方法偵測極限、檢量線範圍、分析穩定性及干擾因素等。微透析技術氯酚類作業環境測定Microdialysis technologyChlorophenolsWorkplace monitoringProject