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  1. Home
  2. Chung Shan Medical University
  3. Project/研究計畫(老師)
  4. 高劑量N-乙酰半胱氨酸的毒性效應與合併類黃酮輔助治療乙醯胺酚誘導急性肝損傷小鼠的最佳治療劑量組合及分子機制
 
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高劑量N-乙酰半胱氨酸的毒性效應與合併類黃酮輔助治療乙醯胺酚誘導急性肝損傷小鼠的最佳治療劑量組合及分子機制

  • Details
Project title
110學年度教學研究計畫
Acronym
教學研究計畫
Principal Investigator
王淑紅  
Start Date
August 1, 2021
Organizations
College of Medical Science and Technology  
Department of Biomedical Sciences  
Partner Organizations
National Science and Technology Council  
Keywords
乙醯胺基苯酚
舒疼
藥物誘導肝損傷
急性肝衰竭
N-乙酰半胱氨酸
微泡性脂肪變性
系統性發炎
肝臟發炎
脂肪代謝
脂肪酸
總膽固醇
甘油三酯
腎損傷
脾臟損傷
半致死劑量
Description
計畫名稱:高劑量N-乙酰半胱氨酸的毒性效應與合併類黃酮輔助治療乙醯胺酚誘導急性肝損傷小鼠的最佳治療劑量組合及分子機制
成果報告:
執行起迄:2021/08/01~2023/01/31
總核定金額:950,000元 (各年度經費明細)
計畫概述:APAP是常用解熱鎮痛藥物之一,取得相當方便,因此不小心就容易攝食過量,80%藥物造成的肝衰竭的病患是因為APAP造成的,臨床上的標準治療藥物是N-乙醯半胱氨酸(N-acetyl cystei...(詳)
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