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Chung Shan Medical University
Project/研究計畫(老師)
PRMT1 催化之蛋白質精胺酸甲基化對壓力顆粒及旁斑點組成及肌萎縮側索硬化症病因關聯
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PRMT1 催化之蛋白質精胺酸甲基化對壓力顆粒及旁斑點組成及肌萎縮側索硬化症病因關聯
Details
Primary Data
Project title
106學年度國家科學及技術委員會補助研究計畫
Acronym
專題研究計畫
Principal Investigator
LI, Chuan
Status
research project
Start Date
2017
End Date
2018
Organizations
Department of Biomedical Sciences
Partner Organizations
National Science and Technology Council
Description
Keywords
蛋白質精胺酸甲基化
蛋白質精胺酸甲基轉移酶1
旁斑點
細胞核旁斑點組合轉錄物1
Description
肌萎縮性側索硬化(ALS)的致病原因與細胞內沒有膜外包的次胞器如核醣蛋白顆粒(RNP)的形成調節有關。多數RNP 顆粒內的 RNA 結合蛋白同時也在 ALS 病人運動神經元的堆積中發現。這些蛋...(詳)
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