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  1. Home
  2. Chung Shan Medical University
  3. Project/研究計畫(老師)
  4. 探討N-乙酰半胱氨酸降低舒疼誘導急性肝損傷小鼠的劑量效應與合併類黃酮輔助治療的可能機制 (II)
 
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探討N-乙酰半胱氨酸降低舒疼誘導急性肝損傷小鼠的劑量效應與合併類黃酮輔助治療的可能機制 (II)

  • Details
Project title
109學年度教學研究計畫
Acronym
教學研究計畫
Principal Investigator
王淑紅  
Start Date
August 1, 2020
Organizations
College of Medical Science and Technology  
Department of Biomedical Sciences  
Partner Organizations
National Science and Technology Council  
Keywords
乙醯胺基苯酚
舒疼
藥物誘導肝損傷
急性肝衰竭
N-乙酰半胱氨酸
微泡性脂肪變性
系統性發炎
肝臟發炎
脂肪代謝
脂肪酸
總膽固醇
甘油三酯
高良薑素
山奈酚
槲皮素
類黃酮
細胞色素P450
抗氧化
抗發炎
細胞壞死
Description
計畫名稱:探討N-乙酰半胱氨酸降低舒疼誘導急性肝損傷小鼠的劑量效應與合併類黃酮輔助治療的可能機制 (II)
成果報告:
執行起迄:2020/08/01~2021/12/31
總核定金額:1,050,000元 (各年度經費明細)
計畫概述:NAC是APAP誘導急性肝衰竭的治療用藥,本研究探討NAC劑量與治療時間對於APAP中毒小鼠肝臟再生的影響,將可以提供臨床上病人最適合的NAC劑量與治療時間的參考。探討類黃酮輔助NAC治療的可...(詳)
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