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  4. 應用穩定同位素標定追蹤技術探討檳榔特有亞硝胺生成路徑及其特有基因鍵結物
 
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應用穩定同位素標定追蹤技術探討檳榔特有亞硝胺生成路徑及其特有基因鍵結物

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Project title
109學年度教學研究計畫
Acronym
教學研究計畫
Principal Investigator
張元哲  
Start Date
August 1, 2020
Organizations
College of Health Care and Managemen  
School of Occupational Safety and Health  
Partner Organizations
National Science and Technology Council  
Keywords
口腔癌
檳榔特有生物鹼
亞硝化
檳榔特有亞硝胺
檳榔亞硝胺特有基因鍵結物
高解析質譜儀
穩定同位素標定法
特定質量差異追蹤技術
特定質量差啟動質譜碎裂模式。
Description
計畫名稱:應用穩定同位素標定追蹤技術探討檳榔特有亞硝胺生成路徑及其特有基因鍵結物
成果報告:
執行起迄:2020/05/01~2021/10/31
總核定金額:1,350,000元 (各年度經費明細)
計畫概述:本計畫旨在運用新穎質譜技術探討檳榔嚼食於口腔、胃中產生的致癌物檳榔特有亞硝胺其形成路徑與重要因子,且透過台灣與印度兩大口腔癌盛行國家的檳榔嚼塊與嚼食者唾液,了解不同國家檳榔嚼塊與致癌物生成的因...(詳)
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