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  1. Home
  2. Chung Shan Medical University
  3. Project/研究計畫(老師)
  4. 檳榔鹼及其氧化物之代謝與毒性作用機制探討
 
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檳榔鹼及其氧化物之代謝與毒性作用機制探討

  • Details
Project title
104學年度國家科學及技術委員會補助研究計畫
Acronym
專題研究計畫
Principal Investigator
Wang, Tsu-Shing  
Status
research project
Start Date
2015
End Date
2016
Organizations
Department of Biomedical Sciences  
Partner Organizations
National Science and Technology Council  
Keywords
檳榔鹼
檳榔鹼N-氧化物
大鼠肝臟clone 9細胞
人類肝臟WRL 68細胞
DNA鏈斷裂
ROS
細胞色素P450
含黃素單加氧酶
粒線體
Description
國際癌症研究機構已將檳榔歸類為人類環境致癌物。以前的研究表明,檳榔鹼是存在於嚼食檳榔者唾液中主要的生物鹼。多年來,研究證據證實,唾液中含有大量檳榔鹼將導致口腔粘膜細胞突變,引發口腔癌。檳榔鹼也...(詳)
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