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  1. Home
  2. Chung Shan Medical University
  3. Project/研究計畫(老師)
  4. 益生菌及其代謝產物對順鉑誘導的腎衰老和腎纖維化之保護作用與相關分子機制以及順鉑、D-甲硫胺酸和益生菌對腸道菌代謝碳源物質之研究
 
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益生菌及其代謝產物對順鉑誘導的腎衰老和腎纖維化之保護作用與相關分子機制以及順鉑、D-甲硫胺酸和益生菌對腸道菌代謝碳源物質之研究

  • Details
Project title
109學年度教學研究計畫
Acronym
教學研究計畫
Principal Investigator
歐珠琴  
Start Date
August 1, 2020
Organizations
College of Health Care and Managemen  
Department of Nutritional Science  
Partner Organizations
National Science and Technology Council  
Keywords
丁酸
順鉑
抗腎臟纖維化
腎毒性及腸道菌相失衡
Description
計畫名稱:益生菌及其代謝產物對順鉑誘導的腎衰老和腎纖維化之保護作用與相關分子機制以及順鉑、D-甲硫胺酸和益生菌對腸道菌代謝碳源物質之研究
成果報告:
執行起迄:2020/08/01~2021/10/31
總核定金額:1,150,000元 (各年度經費明細)
計畫概述:本計畫的目的即利用化療動物模式驗證,益生菌及其代謝產物短鏈脂肪酸可否透過重建腸道菌群結構,增加有益菌及短鏈脂肪酸生成降低致病菌來誘導多重調節功能,進而達到減緩cisplatin誘發的腸道黏膜炎...(詳)
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